CD44: A Multifaceted Molecule in Cancer Progression
نویسنده
چکیده
CD44, a single pass transmembrane glycoprotein, initially characterized as lymphocyte homing receptor, has now been implicated in various stages of cancer development. The Anomaly in CD44 expression distinguishes most human cancers. CD44 is also identified as cancer stem cell marker. This review will comprehend the versatile role of CD44 during cancer initiation, proliferation, invasion, metastasis and as the regulator of cancer cell metabolism.
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